BATL (Biopharmaceutical Analysis & Training Lab)

Man working in a lab

This ICBM lab focuses on technology, innovation, and partnership at the intersection of workforce development, entrepreneurship and use-inspired research. More specifically the research done within BALT focuses on process improvements and product improvements from drug discovery to commercialization. The training programs focus on high school to adult learning programs with an emphasis on chemistry, manufacturing, and control (CMC) across the regulatory landscape. BATL is an APEC Center of Regulatory Excellence in Biotherapeutics and Advanced Therapies, an ICH trusted training provider, and a member of the WHO CIP network.

The BATL Lab emphasizes technology and innovation and is home to one of the most noteworthy pieces of equipment used in research – the Analytical Mass Spectrometry equipment. This specialized tool is useful for measuring the mass-to-charge ratio (m/z) of one or more molecules present in a sample. These measurements can then analyze those ions to provide information about the molecular weight of the compound and its chemical structure.

Additionally, the BATL Lab contains the clinical PCR units including dPCR, and the NGS (Next Generation Sequencing) instruments. BATL is also home to three other unique pieces of lab equipment; the Ambr250 which is a high throughput automated parallel single-use bioreactor equipment used in process development and process optimization as well as in scaling experimentation; Quality Control equipment such as the fragment analyzer and tapestation, used to verify the quality of extracted nucleic material for downstream analytics; and the Flow Cytometry and xCelligence, used to provide cellular analytics such as cellular viability, metabolism, contractility, and cellular movement.